Figure 2.

HB treatment reduces cellular proliferation after H₂O₂-induced oxidative stress.

Notes: Cell-cycle analysis indicated that the percentage of cells in phase G2/S increased after treatment with H₂O₂, but it was significantly lower when cells had been pretreated with HB. Untreated cells (not treated with HB or H₂O₂) were considered as negative controls. Data are given as mean ± SEM of three independent experiments. Statistical analysis: one-way ANOVA (n = 3). Significantly different from H₂O₂ (*p < 0.05).

Abbreviations: HB, hyaluronic acid and butyric acid; SEM, standard error of the mean; ANOVA, analysis of variance.