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. 2017 Sep 8;12:6705–6719. doi: 10.2147/IJN.S146742

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© 2017 Duan et al. This work is published and licensed by Dove Medical Press Limited

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Therapeutic effects of transplanted MSCs.

Notes: Longitudinal coronal T2WI shows that the infarcted hemisphere in animals grafted with polymersome-labeled GFP-MSCs (A), unlabeled GFP-MSCs (B), and PBS (C) exhibited hyperintense signals. Graphs show the measured infarct volume (D) and modified neurologic severity scores (E) among the three groups. *p<0.05 between labeled GFP-MSCs and PBS; ^#p<0.05 between unlabeled GFP-MSCs and PBS.

Abbreviations: mNSS, modified neurological severity score; MSC, mesenchymal stem cell; PBS, phosphate-buffered saline.