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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Mod Pathol. 2016 Jul 29;29(11):1358–1369. doi: 10.1038/modpathol.2016.125

Figure 1.

Figure 1

Pancreatic ductal adenocarcinoma (PDAC, red), ampullary carcinoma (AC, blue), and distal common bile duct carcinoma (DCBDC, green) all arise within close proximity to one another and can therefore overlap in terms of the anatomic space they occupy. Furthermore, PDAC can secondarily involve the ampulla or common bile duct, and AC and DCBDC can similarly invade structures from which they did not originate. Careful consideration of the size, epicenter, presentation, and histology of each lesion should allow for accurate diagnosis.