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. 2017 Sep 8;10:4379–4391. doi: 10.2147/OTT.S143518

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© 2017 Hu et al. This work is published and licensed by Dove Medical Press Limited

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Effects of DEPTOR knockdown on the VM formation and invasion capacity of osteosarcoma cells.

Notes: (A) Images of tube-like structures in MNNG/HOS and MG63 cells transfected with NC siRNA or DEPTOR siRNA, original magnification: ×100. (B) Mean number of tube-like structures in MNNG/HOS and MG63 cells. Data are expressed as mean ± SD of three independent experiments. (C) Micrographs of the Transwell invasion assay in the MNNG/HOS and MG63 cells, original magnification: ×100. (D) Number of invaded cells. Data are expressed as mean ± SD of three independent experiments (**P<0.01, ***P<0.001 compared with nonspecifc siRNA group).

Abbreviations: DEPTOR, DEP-domain containing mTOR-interacting protein; NC siRNA, nonspecific siRNA; VM, vasculogenic mimicry.