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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Bone. 2017 Jun 6;103:20–30. doi: 10.1016/j.bone.2017.06.003

Figure 4. Transcriptome analysis of primary pre-osteoblasts (T5) shows downregulation of genes related to bone mineralization.

Figure 4

(A) Scatterplot representation of log2 expression values (FDR<5% and 1.5 fold change are shown in red). (B) Heatmap representation of differentially expressed genes (FDR<5% and 1.5 fold change), with (C) the most enriched Gene Ontology categories according to DAVID analysis. (D) qPCR validation of bone-related transcripts. Predicted transcription factors associated with upregulated (E) and downregulated (F) genes.