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. Author manuscript; available in PMC: 2018 Apr 18.
Published in final edited form as: Chem Soc Rev. 2017 Apr 18;46(8):2038–2056. doi: 10.1039/c6cs00803h

Figure 5.

Figure 5

(a) Schematic of a method of in vivo CTC capture and enrichment based on transfusion with a vein indwelling needle. (b) Optimization of the antibody adsorbing on the needle via the fluorescence intensity and cell number of the CTCs captured using the nude or PDMS coated vein indwelling needles that are modified with various concentration of anti-EpCAM antibody. The error bars were estimated from three replicate measurements. (c) Microscope images of the DAPI stained MCF-7 cells captured on the needle. Reproduced from reference 32 with permission from American Chemical Society, copyright 2015.