TABLE A1.
Visual Analog Scale Scores for Pain (in mm)
| rhBMP-12/ACS | Standard of Care | |
|---|---|---|
| Before surgery | ||
| No. of patients | 16 | 4 |
| Mean | 37.9 | 48.3 |
| Median | 22.5 | 50.0 |
| SD | 30.3 | 24.2 |
| Range | 7-97 | 17-76 |
| 12 wk after surgery | ||
| No. of patients | 16 | 3 |
| Mean | 23.2 | 12.0 |
| Median | 10.5 | 12.0 |
| SD | 30.5 | 9.0 |
| Range | 0-100 | 3-21 |
| 16 wk after surgery | ||
| No. of patients | 16 | 3 |
| Mean | 19.9 | 2.7 |
| Median | 7.5 | 3.0 |
| SD | 27.1 | 2.5 |
| Range | 0-85 | 0-5 |
| 26 wk after surgery | ||
| No. of patients | 16 | 3 |
| Mean | 24.2 | 7.0 |
| Median | 8.5 | 2.0 |
| SD | 33.2 | 10.4 |
| Range | 0-93 | 0-19 |
| 39 wk after surgery | ||
| No. of patients | 15 | 2 |
| Mean | 12.6 | 2.0 |
| Median | 10.0 | 2.0 |
| SD | 14.3 | 1.4 |
| Range | 0-50 | 1-3 |
| 52 wk after surgery | ||
| No. of patients | 15 | 2 |
| Mean | 13.8 | 1.5 |
| Median | 1.0 | 1.5 |
| SD | 25.6 | 0.7 |
| Range | 0-80 | 1-2 |