TABLE A5.
rhBMP-12/ACS | Standard of Care | |||
---|---|---|---|---|
Active | Passive | Active | Passive | |
Before surgery | ||||
No. of patients | 16 | 16 | 4 | 4 |
Mean | 61.9 | 70.8 | 62.5 | 72.0 |
Median | 62.5 | 70.0 | 65.0 | 77.5 |
SD | 11.1 | 10.5 | 17.1 | 22.6 |
Range | 30-75 | 55-90 | 40-80 | 43-90 |
12 wk after surgery | ||||
No. of patients | 16 | 16 | 3 | 3 |
Mean | 49.3 | 55.6 | 46.7 | 55.7 |
Median | 50.0 | 62.5 | 40.0 | 45.0 |
SD | 19.5 | 20.5 | 30.6 | 30.4 |
Range | 10-75 | 15-85 | 20-80 | 32-90 |
16 wk after surgery | ||||
No. of patients | 16 | 16 | 3 | 3 |
Mean | 52.1 | 59.7 | 43.0 | 53.0 |
Median | 56.0 | 62.5 | 40.0 | 45.0 |
SD | 15.7 | 17.5 | 15.7 | 14.7 |
Range | 30-76 | 30-82 | 29-60 | 44-70 |
26 wk after surgery | ||||
No. of patients | 16 | 16 | 3 | 3 |
Mean | 58.6 | 65.6 | 48.3 | 55.0 |
Median | 64.0 | 65.0 | 45.0 | 50.0 |
SD | 16.6 | 16.2 | 10.4 | 13.2 |
Range | 30-85 | 30-90 | 40-60 | 45-70 |
39 wk after surgery | ||||
No. of patients | 15 | 15 | 2 | 2 |
Mean | 62.9 | 66.7 | 39.0 | 45.5 |
Median | 66.0 | 72.0 | 39.0 | 45.5 |
SD | 21.7 | 21.4 | 1.4 | 0.7 |
Range | 20-90 | 30-90 | 38-40 | 45-46 |
52 wk after surgery | ||||
No. of patients | 15 | 15 | 2 | 2 |
Mean | 61.9 | 67.3 | 45.0 | 50.0 |
Median | 70.0 | 72.0 | 45.0 | 50.0 |
SD | 21.8 | 20.2 | 7.1 | 0.0 |
Range | 10-90 | 20-90 | 40-50 | 50-50 |