Table 2.

Differences between dogs with adverse events and dogs without adverse events associated with the use of leflunomide. Data are reported as medians with ranges

	Adverse events (n = 11)	No adverse events (n = 81)	P
Age (years)	9 (3–14)	7 (1–14)	0.31
Body weight (kg)	27 (8–44.0)	23.4 (4.8–71.5)	0.92
BSA (m2)	0.92 (0.32–1.27)	0.84 (0.29–1.76)	0.44
Sex	Male (n = 6)	Male (n = 32)	0.53
	Female (n = 5)	Female (n = 49)
Breed	Mixed breed (n = 5)	Mixed breed (n = 19)	0.23
	Purebreds (n = 6)	Purebreds (n = 62)
Leflunomide dosage (mg/kg/d)	2.9 (1.8–3.6)	1.6 (0.8–4.3)	<0.001