Table 2.
Correlation coefficient (r), regression coefficient (β), and 95% confidence interval for β for combinations of oral sugar test derived indices of β‐cell response and euglycemic hyperinsulinemic clamp derived sensitivity measures used in the regression model: Ln (y) = constant + β × Ln (x). Three of the 49 horses had a delayed early glucose and/or insulin responses during OST, resulting in missing data for INSINDEX and AUCINS/GLU‐30
| β‐cell response | Sensitivity measures | r | β (95% CI) |
|---|---|---|---|
| PeakINS | M | −0.84 | −1.30 (−1.50 to −1.10) |
| PeakINS | M/I | −0.84 | −1.03a (−1.22 to −0.90) |
| INSINDEX | M | −0.77 | −1.03a (−1.32 to −0.92) |
| INSINDEX | M/I | −0.87 | −1.10a (−1.30 to −0.99) |
| AUCINS‐180 | M | −0.87 | −1.40 (−1.62 to −1.19) |
| AUCINS‐180 | M/I | −0.86 | −1.12a (−1.35 to −0.96) |
| AUCINS/GLU‐30 | M | −0.77 | −1.04a (−1.33 to −0.80) |
| AUCINS/GLU‐30 | M/I | −0.73 | −0.80a (−1.01 to −0.59) |
| AUCINS/GLU‐120 | M | −0.81 | −1.17a (−1.44 to −1.00) |
| AUCINS/GLU‐120 | M/I | −0.80 | −0.92a (−1.19 to −0.83) |
| AUCINS/GLU‐180 | M | −0.81 | −1.16 (−1.43 to −1.02) |
| AUCINS/GLU‐180 | M/I | −0.80 | −0.91a (−1.17 to −0.82) |
PeakINS, peak insulin concentration during OST; INSINDEX, insulinogenic index; AUCINS‐180, incremental area under the curve for insulin at 180 min of OST; AUCINS/GLU‐30, incremental area under the curve for insulin/glucose at 30 min of OST; AUCINS/GLU‐120, incremental area under the curve for insulin/glucose at 120 min of OST; AUCINS/GLU‐180, incremental area under the curve for insulin/glucose at 180 min of OST; M, mean insulin‐dependent glucose disposal rate; M/I, mean insulin‐dependent glucose disposal rate per unit of insulin.
Indicate rectangular hyperbolic relationship within row (P < 0.05).