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. 2017 Sep 14;12(9):e0183159. doi: 10.1371/journal.pone.0183159

Table 3. Loadings of individual cell, microvesicles and cell-cell interaction parameters on principal components.

Measure Loadings: PC#1 PC#2 PC#3 PC#4 PC#5 PC#6 PC#7
Blood cells
Blood platelet count 0.41
Total white blood cell count 0.43
Granulocyte count 0.38
Lymphocyte count 0.35
Monocyte count
Platelet characteristics
Mean platelet volume -0.49
Whole blood platelet aggregation 0.34
ATP Secretion 0.44 -0.24
Basal expression of phosphatidylserine (annexin-V) 0.25 -0.22
Basal expression of P-selectin 0.28 0.29
Basal expression of fibrinogen receptor (PAC-1) 0.25
Blood-borne microvesicles
Platelet-derived (CD42a) -0.33 0.24
Leukocyte-derived (CD45) 0.22 0.23
Erythrocyte-derived (CD235a) -0.25
Endothelium-derived (CD62E) 0.34
Smooth muscle cell-derived (SM22α) 0.25
Stem/progenitor cell (CD117) -0.23
Adipocyte-derived (Pref-1) 0.31
Senescent cell-derived (P16-set) 0.33
Inter cellular adhesion molecule-1 (ICAM-1) 0.29
Vascular cell adhesion molecule-1 (VCAM-1) 0.33
Phosphatidylserine (annexin-V) -0.35 0.21
Tissue factor 0.27 -0.23
Interactions among cellular elements
Platelets pos. for leukocyte (CD45)
Platelets pos. for granulocyte (CD15) 0.25 -0.22
Platelets pos. for monocyte (CD14) 0.27
Platelets pos. for T-lymphocyte (CD3) 0.26 -0.49
Platelets pos. for B-lymphocyte (CD19) 0.29 -0.42
Platelets pos. for endothelial (CD62E) 0.29
Granulocytes pos. for phosphatidylserine (annexin-V) 0.28 -0.22 0.30
Granulocytes pos. for platelets (CD42a) 0.29 0.23
Granulocytes pos. for endothelium (CD62E) 0.28 -0.22 0.27
Monocytes pos. for phosphatidylserine (annexin-V) 0.30 0.20
Monocytes pos. for platelets (CD42a) 0.31 0.27 0.31
Monocytes pos. for endothelium (CD62E) 0.31
Lymphocytes pos. for phosphatidylserine (annexin-V)
Lymphocytes pos. for platelets (CD42a) 0.21
Lymphocytes pos. for endothelium (CD62E) 0.22
Proportion 19.1% 12.7% 8.6% 7.2% 6.0% 5.1% 4.6%
Cumulative 19.1% 31.8% 40.4% 47.6% 53.6% 58.7% 63.3%