Table 2. Summary of miRNAs and their targets predicted from in silico analyses based on TCGA database.
MicroRNA | Fold-changea | Predicted target genes |
---|---|---|
hsa-miR-133a-3p | 0.28 | AMACR, BCL2, COL1A1, NKX3-1, SIM2 |
hsa-miR-133b | 0.27 | AMACR, BCL2, COL1A1, NKX3-1, SIM2 |
hsa-miR-143-3p | 0.40 | AMACR, BCL2, COL1A1, GOLM1, MPM11, NKX3-1, OR51E2, SIM2 |
hsa-miR-183-5p | 4.35 | AMACR, COL1A1, FOXA1, MPM11, NKX3-1, TRPM8 |
hsa-miR-200b-3bb | - | AMACR, BCL2, GOLM1, OR51E2, SIM2, TRPM |
hsa-miR-200c-3p | 3.33 | AMACR, BCL2, FOXA1, GOLM1, OR51E2, SIM2, TRPM8 |
hsa-miR-205-5p | 0.36 | AMACR, BCL2, COL1A1, GOLM1, MPM11, NKX3-1, SIM2, TRPM8 |
hsa-miR-375 | 6.74 | AMACR, BCL2, COL1A1, FOXA1, GOLM1, NKX3-1, SIM2, TRPM8 |
aFold-change based on The Cancer Genome Atlas (TCGA) data; tumor tissue versus normal tissue.
bmiRNA selected after investigation in the literature of the candidate miRNAs in prostate cancer