Table 3. Demographic, clinical, and laboratory values in 142,412 according to type of dialyzer membrane.
| CTA | EVAL | PAN | PEPA | PES | PMMA | PS | P value | |
|---|---|---|---|---|---|---|---|---|
| n (%) | 24,572 (17.3) | 1,604 (1.1) | 1,703 (1.2) | 10,677 (7.5) | 17,060 (12.0) | 6,954 (4.9) | 79,842 (56.0) | |
| Total deaths (n) | 2,167 | 270 | 144 | 889 | 951 | 603 | 5,139 | |
| Death rate (per 100 patient-years) | 8.82 | 16.8 | 8.45 | 8.33 | 5.57 | 8.67 | 6.44 | <0.0001 |
| Age (years) | 67 ± 12 | 72 ± 11 | 67 ± 12 | 66 ± 12 | 63 ± 12 | 68 ± 12 | 64 ± 12 | <0.0001 |
| Sex (% female) | 39.5 | 55.7 | 46.7 | 41.4 | 35.2 | 43 | 38.7 | <0.0001 |
| Dialysis duration (years) | 6 [3–10] | 5 [3–9] | 7 [4–12] | 6 [3–11] | 7 [4–13] | 6 [4–11] | 7 [4–13] | <0.0001 |
| Presence of DM (%) | 35.7 | 35.5 | 31.4 | 32.3 | 28.6 | 33.2 | 29.2 | <0.0001 |
| Comorbidity of CVD (%) | 26.7 | 33.8 | 24.7 | 25.6 | 22.4 | 28.8 | 23.9 | <0.0001 |
| Body mass index (kg/m2) | 21.0 ± 3.6 | 20.0 ± 3.4 | 20.7 ± 3.3 | 20.9 ± 3.4 | 21.4 ± 3.5 | 20.6 ± 3.2 | 21.1 ± 3.5 | <0.0001 |
| Hemoglobin (g/dL) | 10.4 ± 1.3 | 10.2 ± 1.3 | 10.2 ± 1.2 | 10.4 ± 1.3 | 10.5 ± 1.2 | 10.2 ± 1.2 | 10.5 ± 1.2 | <0.0001 |
| Serum albumin (g/dL) | 3.7 ± 0.4 | 3.5 ± 0.5 | 3.7 ± 0.4 | 3.6 ± 0.4 | 3.8 ± 0.4 | 3.6 ± 0.4 | 3.7 ± 0.4 | <0.0001 |
| Total cholesterol (mg/dL) | 155 ± 36 | 162 ± 40 | 153 ± 35 | 157 ± 37 | 152 ± 35 | 162 ± 38 | 151 ± 36 | <0.0001 |
| Calcium (mg/dL) | 9.0 ± 0.8 | 8.9 ± 0.8 | 9.1 ± 0.9 | 9.0 ± 0.8 | 9.1 ± 0.8 | 8.9 ± 0.8 | 9.1 ± 0.8 | <0.0001 |
| Phosphate (mg/dL) | 5.3 ± 1.4 | 5.0 ± 1.4 | 5.3 ± 1.5 | 5.3 ± 1.4 | 5.4 ± 1.5 | 5.2 ± 1.4 | 5.3 ± 1.4 | <0.0001 |
| β2-microglobulin (mg/L) | 27.8 ± 7.0 | 29.8 ± 8.0 | 30.0 ± 7.0 | 27.1 ± 6.5 | 27.2 ± 6.5 | 29.5 ± 7.0 | 27.2 ± 6.5 | <0.0001 |
| C-reactive protein (mg/dL) | 0.13 [0.06–0.4] | 0.16 [0.06–0.59] | 0.13 [0.06–0.39] | 0.12 [0.05–0.38] | 0.10 [0.05–0.31] | 0.13 [0.05–0.40] | 0.11 [0.05–0.36] | <0.0001 |
| Surface area of dialyzer (m2) | 1.6 ± 0.4 | 1.4 ± 0.3 | 1.4 ± 0.2 | 1.6 ± 0.3 | 1.8 ± 0.3 | 1.6 ± 0.3 | 1.7 ± 0.3 | <0.0001 |
| Characteristic of dialyzer (%) | <0.0001 | |||||||
| Low flux | 1.7 | 36.1 | 0 | 0 | 0 | 1.0 | 0 | |
| High flux | 98.3 | 63.9 | 100 | 100 | 100 | 99.0 | 100 | |
| Kt/V | 1.41 ± 0.28 | 1.30 ± 0.28 | 1.39 ± 0.29 | 1.42 ± 0.28 | 1.46 ± 0.29 | 1.39 ± 0.27 | 1.45 ± 0.29 | <0.0001 |
| nPCR (g/kg/day) | 0.87 ± 0.18 | 0.85 ± 0.18 | 0.88 ± 0.18 | 0.88 ± 0.18 | 0.90 ± 0.18 | 0.86 ± 0.18 | 0.90 ± 0.18 | <0.0001 |
| %CGR (%) | 97 ± 26 | 85 ± 30 | 96 ± 27 | 99 ± 26 | 102 ± 24 | 96 ± 26 | 101 ± 25 | <0.0001 |
CTA, cellulose triacetate; CVD, cardiovascular disease; DM, diabetes mellitus; EVAL, ethylene vinyl alcohol; nPCR, normalized protein catabolic rate; PAN, polyacrylonitrile; PEPA, polyester polymer alloy; PES, polyethersulfone; PMMA, polymethylmethacrylate; PS, polysulfone, %CGR, % creatinine generation rate.