Table 1. Microglia cell body:total coverage ratio based on Iba-1 immunohistochemistry.
Mean ± sem | p-value | ||||||
---|---|---|---|---|---|---|---|
CON + sham | CSS + sham | CON + ECS | CSS + ECS | Interaction | Main effect | ||
Group | Treatment | ||||||
CA1oriens | 0.016± 0.003 | 0.024± 0.004 | 0.021± 0.004 | 0.023± 0.003 | 0.38 | 0.18 | 0.47 |
CA1radiatum | 0.018 ± 0.003 | 0.021± 0.001 | 0.026± 0.002 | 0.025± 0.002 | 0.35 | 0.65 | 0.01* |
CA3oriens | 0.021 ±± 0.002 | 0.023± 0.002 | 0.024± 0.002 | 0.020± 0.002 | 0.16 | 0.66 | 0.86 |
CA3radiatum | 0.017 ± 0.002 | 0.019± 0.002 | 0.021± 0.001 | 0.024± 0.002 | 0.98 | 0.17 | 0.01* |
Dentategyrus | 0.025 ± 0.003 | 0.030± 0.003 | 0.032± 0.002 | 0.028± 0.002 | 0.96 | 0.32 | 0.28 |
Hilus | 0.032 ± 0.005 | 0.036± 0.003 | 0.036± 0.003 | 0.040± 0.003 | 0.87 | 0.28 | 0.83 |
PFC | 0.030 ± 0.005 | 0.033± 0.003 | 0.030± 0.003 | 0.034± 0.002 | 0.08 | 0.87 | 0.30 |
VTA | 0.010 ± 0.002 | 0.009± 0.002 | 0.010± 0.002 | 0.009± 0.001 | 0.90 | 0.76 | 0.85 |
PFC = prefrontal cortex; VTA = ventral tegmental area.
Asterisks represent significance
*p<0.05.