Skip to main content
. 2017 Sep 14;12(9):e0184811. doi: 10.1371/journal.pone.0184811

Fig 4. Time course of microglial phenotype after mild TBI.

Fig 4

Quantification of pro-inflammatory (Il1b, Tnfa, Ptgs2, Cd32 and Cd86 mRNA), anti-inflammatory (Lgals3, Igf1, Cd206 and Il10 mRNA) and immunoregulatory markers (Il1rn, Il4ra and Socs3 mRNA) by RT-qPCR in CD11b+ cells magnetically sorted from brain of sham-operated and TBI mice at 6 hours, 1, 2, 3 and 7 days post-injury. mRNA expression was presented as a fold change relative to sham-operated mice. Data were expressed as means ± S.E.M. Differences were analyzed by 2-way ANOVA with subsequent group comparisons by Dunnett test with Bonferroni correction. * p<0.05, ** p<0.01 *** p<0.001 vs sham-operated.