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NK cell degranulation correlates with elotuzumab concentration. A) Percentage CD56dim NK cells in PBMC from 3 healthy donors degranulating after 2 hours with various concentrations (0.001–100µg/ml) of Elo alone (left) or with MM.1R targets (right; PBMC to target cell ratio 1:1). B) Viability of CD56dim NK cells as the percentage of propidium iodide (PI)-negative CD56dim NK cells for each condition.
