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. Author manuscript; available in PMC: 2017 Sep 14.
Published in final edited form as: Dev Biol. 2017 Jul 23;429(1):44–55. doi: 10.1016/j.ydbio.2017.07.011

Fig. 4. Irx1 ablation leads to neonatal lethality and lung defects.

Fig. 4

(A) Representative image of Irx1+/+ and Irx1−/− pups right after birth. Irx1+/+ pup has milk in stomach (indicated by asterisk). (B) Representative image of lung from Irx1+/+ and Irx1−/− mice at P0. The lung from Irx1−/− mouse is smaller compared to the lung Irx1+/+ mouse. (C) Total body weight of Irx1 new born pups. (D) Representative hematoxylin & eosin staining images of the left lung from E16.5 embryos. Histological structure of the lung from Irx1−/− embryos is similar to the lung from Irx1+/+ embryos. (E) Histological analysis of lung from E18.5 and P0 Irx1+/+ and Irx1−/− mice. E18.5 and P0 embryos were fixed and the left lung was used for analysis. Scale bar: 200 μm (D), 50 μm (E).