Figure 7. Immune cell frequency comparison.

(A) Blue and red diamond indicate individual primary and recurrent tumors. Dash line connects paired primary and recurrent tumors. (B) Blue and red circle indicate non-hypermutated and hypermutated primary samples. (C) Sky blue/dark blue and orange/red boxplots indicate short- and long- term relapsed tumors, respectively. y-axis stands for immune cell fraction. Wilcoxon rank tests were used to examine the significance of the differences between groups, and p values were shown at top of each panel. Boxplots represent 25^th and 75^th percentiles, with midlines indicating the median values and points within the boxes indicating the mean values. Whiskers extend to the lowest/highest values of the data sample exculding outliers (A-C). See also Figure S6 and Table S7.