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. Author manuscript; available in PMC: 2017 Sep 14.
Published in final edited form as: Transl Brain Rhythm. 2017 Jul 27;2(1):10.15761/TBR.1000114. doi: 10.15761/TBR.1000114

Figure 2. Effects of cocaine and methylphenidate (MPH) binge treatment on peak amplitude and area of F(Ratio) using bis-fura 2 in ventrobasal (VB) neurons.

Figure 2

A, B, mean baseline F(Ratio) (shown as percentage of saline values) recorded from soma or dendrites, respectively. ** represents P<0.001 comparing cocaine vs. saline, MPH; # represents P<0.05 comparing MPH vs. saline. C, D, mean peak amplitude F(Ratio) from soma or dendrites, respectively, of VB neurons from mice treated with saline, cocaine or MPH binge treatments. Peak amplitudes were obtained immediately after 500 ms square pulses that changed holding potential from −70 mV to either −30 mV or −10 mV. * represents P<0.05. E, F, mean areas (i.e., time-integral of F(Ratio) signals) from soma or dendrites, respectively, of VB neurons from mice treated with saline, cocaine or MPH binge treatments. Peak amplitudes were obtained immediately after 500 ms square pulses that changed holding potential from −70 mV to either −30 mV or −10 mV. * represents P<0.05.