Table 1.

Summary of adverse events

Adverse Event (n = 17 patients)	Grade 1	Grade 2	Grade 3	Grade 4	Grade 5	Total
Blood and lymphatics
Anemia		2				2
Leukocytosis	1					1
Cardiac
Chest pain	1	1	1			3
Sinus tachycardia	1		1	1		3
Superior vena cava and brachiocephalic vein stenosis			1			1
Gastrointestinal
Abdominal pain	2					2
Dysphagia	1					1
Constipation	2					2
Gastroesophageal reflux disease	1					1
Hematemesis	1					1
Nausea	3†		1			4
Vomiting			1			1
General
Cachexia	1					1
Edema	1	1	1			3
Fever	1					1
Fatigue	2†	3	3	1		9
Flu-like symptoms	1†					1
General discomfort/pain	1		1			2
Night sweats		1				1
Pallid	1					1
Swelling (head)	1					1
Infections and infestations
Sinusitis	1					1
Metabolism and nutrition
Alkalosis	1					1
Alcohol intoxication		1				1
Anorexia	1	1				2
Hypercalcemia	1					1
Hyponatremia	1					1
Musculoskeletal
Fracture (cervical spine)				1		1
Pain/Muscle weakness	1	7	4	1		13
Nervous system						2
Headache	1	1
Stroke					1	1
Psychiatric
Anxiety		3				3
Confusion	1					1
Delirium	1					1
Depression		1				1
Renal and urinary
Nocturia		1				1
Pyuria	1					1
Urinary tract infection	1					1
Respiratory
Blood-tinged sputum after injections	1†
Chronic obstructive pulmonary disease exacerbation			1			1
Dyspnea	2	4	5	1		12
Hypoxia	1		1			2
Pleural effusion	3	1	1			5
Possible pneumonia			1			1
Productive cough	1	3	1			6
Pulmonary hypertension	1					1
Rhonchi	1					1
Sore throat	1					1
Wheezing	1					1
Catheter placement for leukapheresis			2			2
Progressive disease			1	6		7

^†4 adverse events were possibly related to the vaccine