Table 1. Factors influencing risk-benefit analyses of LDCT lung cancer screening.
Subject |
Risk of lung cancer (age, gender, smoking history, additional factor as asbestos exposure etc.) |
Susceptibility to radiation induced cancer (age, gender) |
Screening procedure |
Duration and interval of LDTC screening rounds |
Management of suspicious lesions (follow-up LDCT, FDG-PET, FDG-PET/CT, contrast-enhanced or unenhanced full dose CT, CT-guided diagnostic FNA or core biopsy) |
CT technology |
CT scanner type |
Reconstruction software (conventional, iterative) |
CT technique |
Acquisition protocols (collimation, mAs and kV of the radiation tube) |
LDCT, low dose computed tomography; FNA, fine needle aspiration; FDG-PET, 2-(18F)flu-2-deoxy-D-glucose positron emission tomography.