Table 1. Comparison between the three different protocols of EVLP.
| Parameters | Lund | Toronto | OCS |
|---|---|---|---|
| Perfusion | |||
| Target flow | 40% of CO | 40% of CO | 2–2.5 L/min |
| Pressure | |||
| PA | Flow dictated | ≤20 mmHg | ≤20 mmHg |
| LA | 3–5 mmHg (closed) | 0 mmHg (open) | 0 mmHg (open) |
| Perfusate | Steen TM solution | Steen TM solution and RBCP Hct 14% | OCS TM solution and PRBC Hct 15–25% |
| Pump | Roller | Centrifugal | Piston (pulsatile) |
| Ventilation | |||
| Start temp (°C) | 32 | 32 | 34 |
| Tidal volume | 7 mL/kg | 5–7 mL/kg | 7 mL/kg |
| RR | 7 | 20 | 10 |
| PEEP | 5 cmH2O | 5 cmH2O | 5–7 cmH2O |
| FiO2 (%) | 21 | 50 | 12 |
| Sweep gas flow | Titrate to PA pCO2 34–38 mmHg | Titrate to PA pCo2 34–38 mmHg | |
| Temperature (°C) | |||
| Start of ventilation | 32 | 32 | 32 |
| Start of perfusion | 15 | 25 | 32 |
| Start of evaluation | 37 | 37 | 37 |
EVLP, ex vivo lung perfusion; OCS, Organ Care System; CO, cardiac output; PA, pulmonary artery; LA, left atrial; RBCP, red blood cell products; Hct, hematocrit; RR, respiratory rate; PEEP, positive end expiratory pressure; FiO2, fraction of inspired oxygen.