Table 2.
Kinetic analysis of p.Arg310Gln GARS.
| Variant | kcat (s−1) | Km (μM) | kcat/Km (s−1 μM−1) | Ratio |
|---|---|---|---|---|
| Wild-type | 0.049 ± 0.014 | 0.74 ± 0.30 | 0.066 | 1 |
| p.Arg310Gln | 0.00040 ± 1.0×10−4 | 5.5 ± 2.2 | 7.2×10−5 | 1/920 |
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