A, hypertrophic index was determined by measuring the ratio of right kidney weight (gm) and total body weight (gm) of
the SS rats treated with vehicle (n=7) or rapamycin (n=9) maintained on the 4.0% NaCl diet.
B, graph represents the percentage of p27+ cells (hypertrophy), C, percentage of
Ki67+ cells (cell proliferation) D, quantification of apoptotic cells/mm2 (TUNEL
assay) in the renal cortex and outer medulla of SS rats treated with vehicle (n=6) or rapamycin (n=6) maintained
on the 4.0% NaCl diet. Blue and brown column on bar graph represent cortex and outer medulla, respectively. *
p<0.05 Vs vehicle.