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. 2017 Jul 20;390(10):1047–1059. doi: 10.1007/s00210-017-1406-z

Table 1.

IC50 values of studied inhibitors estimated by non-linear regression using data obtained from in vitro study

Compound PDE4B IC50 (μM) PDE7A IC50 (μM)
R-(-)-LSF 49.1 266.1
S-(+)-LSF 52.5 328.2
PTX 91.3 >500.0
IBMX 46.6 77.7