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Pharmacokinetic profile of omeprazole. Data are mean (+SD) plasma omeprazole concentrations versus time following a single 20-mg dose of omeprazole administered alone (solid line, triangles) and with 10 mg (a) or 25 mg (b) OCA (dotted line, squares). Main figures display omeprazole plasma concentration on a linear scale, and insets display log scale. Includes patients from omeprazole PK population (N = 47)
