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Effect of silencing oxLDL-dependent induction of PCSK9 expression on cell shortening. a Cells were exposed to oxLDL (20 µg/ml) or siRNA directed against PCSK9. Data are mean ± SD from 90 cells each from ten independent experiments. a: p < 0.05 vs. control, siRNA, and oxLDL plus siRNA. b Cell shortening of cells exposed to actinomycin D or cycloheximide with and without oxLDL; a: p < 0.05 vs. all other groups
