Table 2.

Effect of oxLDL (10 µg/ml) on load-free cell shortening

	Control	oxLDL	p value
n	126	117	n.d.
L Diast (µm)	99.89 ± 16.56	99.38 ± 16.64	0.81
Amplitude (µm)	10.85 ± 2.86	8.14 ± 4.05	≤0.00
dL/L (%)	10.89 ± 2.33	8.10 ± 3.69	≤0.00
TTP50 (ms)	64 ± 10	63 ± 10	0.25
TTP (ms)	162 ± 27	151 ± 30	≤0.00
TTP/amplitude (ms/µm)	16.19 ± 6.52	25.71 ± 20.31	≤0.00
Contraction velocity (µm/s)	196 ± 59	155 ± 79	0.00
R50 (ms)	244 ± 36	233 ± 41	0.03
R50/amplitude (ms/µm)	24.48 ± 9.96	40.32 ± 33.14	≤0.00
Relaxation velocity (µm/s)	184 ± 68	152 ± 90	≤0.00

Data are mean ± SD; n = number of cells from three different rats (14 culture dishes)

L Diast diastolic cell length, dL/L shortening amplitude normalized to diastolic cell length (amplitude × 100/L Diast), TTP time to peak, TTP50 time to reach 50% of peak shortening, R50 time to reach 50% of relaxation