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. 2017 Sep 14;7:11551. doi: 10.1038/s41598-017-10443-6

Table 4.

Literature review of the effect of chemical constituents of FAEW against oxidative stress.

Compounds In vitro In vivo
Paeonifloirin Neurotoxicity43; apoptosis4446; oxidative injury47; cell damage48; osteoblast cytotoxicity49 Cholestasis50, chronic obstructive pulmonary disease4
Albiflorin Neurotoxicity51, 52, oxidative stress52 Diabetics53
Baicalin Oxidative injury54, 55; apoptosis56 Colitis57; Haemophilus parasuis infection58; vascular inflammation59; neurotoxicity60; skin fibroblast61
Isoliquiritin Neurotoxicity62 Oxidative stress-induced genotoxicity63
Isoliquiritin apioside Oxidative stress-induced genotoxicity63
Liquiritin Myocardial fibrosis64, depression65, lung epithelial cell injury66, cognitive deficits67, endothelial dysfunction68