Table 4.
Top eight 4-way SNP-combinations with p-values from G-test less than 1e-12 (the last three columns respectively are the p-value of G-test, p-value of chi-square and the prediction accuracy of SVM (Support Vector Machine)).
| SNP1 | SNP2 | SNP3 | SNP4 | 4-way SNP combination | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| name | chrom | p-value | name | chrom | p-value | name | chrom | p-value | name | chrom | p-value | G-test | Chi-sq | SVM |
| rs2157998 | 7 | 8.5E-01 | rs1334722 | 10 | 5.7E-02 | rs1740752 | 10 | 4.0E-05 | rs7104698 | 11 | 1.6E-04 | 2.0E-13 | 0 | 80.8% |
| rs10508291 | 10 | 1.7E-03 | rs417637 | 17 | 2.2E-03 | rs10272438 | 7 | 9.7E-06 | rs10518080 | 4 | 2.5E-02 | 6.5E-13 | 0 | 80.1% |
| rs10489581 | 1 | 2.1E-03 | rs10517007 | 4 | 8.0E-01 | rs10511467 | 9 | 2.9E-05 | rs10507949 | 13 | 6.8E-05 | 6.8E-13 | 0 | 80.8% |
| rs961360 | 2 | 1.0E-03 | rs380390 | 1 | 6.2E-07 | rs10516957 | 4 | 5.1E-03 | rs10501442 | 11 | 9.1E-03 | 6.8E-13 | 0 | 79.5% |
| rs3775652 | 4 | 3.7E-07 | rs1740752 | 10 | 4.0E-05 | rs7104698 | 11 | 1.6E-04 | rs10514569 | 16 | 5.7E-02 | 7.6E-13 | 0 | 77.4% |
| rs10272438 | 7 | 9.7E-06 | rs380390 | 1 | 6.2E-07 | rs10501267 | 11 | 7.1E-01 | rs920799 | 18 | 4.5E-02 | 9.5E-13 | 0 | 81.5% |
| rs10489581 | 1 | 2.1E-03 | rs10511467 | 9 | 2.9E-05 | rs10507949 | 13 | 6.8E-05 | rs1025758 | 4 | 4.0E-03 | 9.6E-13 | 0 | 76.0% |
| rs10272438 | 7 | 9.7E-06 | rs10482918 | 21 | 4.5E-02 | rs200642 | 20 | 3.7E-04 | rs6104678 | 20 | 2.1E-04 | 1.0E-12 | 0 | 78.1% |