Table 2.
Effect of PTT mixture and placebo supplementations for 14 days on platelet activation, haemostatic and inflammatory markers.
PTT Mixture Intervention | Placebo Intervention | P | |
---|---|---|---|
Activated glycoprotein IIb/IIIa receptor (MFI) | 12.37 ± 3.42 | 12.09 ± 3.53 | 0.602 |
sP-selectin (ng/mL) | 93.96 ± 67.53 | 78.60 ± 43.97 | 0.224 |
Fibrinogen (g/L) | 3.00 ± 0.68 | 2.97 ± 0.69 | 0.865 |
D-dimer (ng/mL) | 241.82 ± 170.72 | 287.80 ± 418.08 | 0.505 |
PAI-1 (ng/mL) | 78.69 ± 33.91 | 80.11 ± 33.30 | 0.551 |
ucOC (ng/mL) | 4.74 ± 2.10 | 4.90 ± 1.98 | 0.196 |
hsCRP (mg/L) | 4.81 ± 4.86 | 4.94 ± 4.65 | 0.795 |
sE-selectin (ng/mL) | 43.55 ± 15.02 | 43.45 ± 15.99 | 0.715 |
sICAM-1 (ng/mL) | 220.20 ± 56.62 | 219.20 ± 63.68 | 0.629 |
sVCAM-1 (ng/mL) | 554.60 ± 138.00 | 576.00 ± 149.00 | 0.210 |
Prior to statistical analysis, data for activated glycoprotein IIb/IIIa receptor, fibrinogen, sE-selectin, sICAM-1 and hsCRP were logarithmic transformed. Data for activated glycoprotein IIb/IIIa receptor, fibrinogen, PAI-1, sE-selectin, sICAM-1 and hsCRP were analysed using Student t-test while data for D-dimer, ucOC, sP-selectin and sVCAM-1 were analysed using Wilcoxon Signed rank test. Abbreviation: hsCRP: high sensitivity C-reactive protein, PAI-1: plasminogen activator inhibitor type 1, sE-selectin: soluble E-selectin, sICAM-1: soluble intracellular adhesion molecules 1, sP-selectin: soluble P-selectin, sVCAM-1: soluble vascular cellular adhesion molecules 1, ucOC: undercarboxylated osteocalcin.