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. 2017 Sep 14;7:11580. doi: 10.1038/s41598-017-06674-2

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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ROC curves and calibration plots of the two-cytokine models, including the apparent and bias-corrected measures by bootstrapping. In the calibration plots, the predicted probability of the model is represented on the x-axis and the observed proportion of chronic periodontitis is represented on the y axis. The 45° line indicates perfect congruity between the predicted probability and the observed proportion of chronic periodontitis.