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. Author manuscript; available in PMC: 2017 Sep 15.
Published in final edited form as: Drug Dev Ind Pharm. 2014 Dec 8;41(7):1089–1094. doi: 10.3109/03639045.2014.927481

Table 1.

The solubility of ITR and ITR-HCl (mg/ml) in different solvent systems.

Solubility of ITR and ITR-HCl (mg/ml)

Water Isopropanol Water pH 3 Water:Isopropanol ratio (pH 3)

90:10 80:20 70:30 60:40 50:50
ITR 0.288 0.112 0.207
ITR-HCl 0.01 15.15 0.04 0.06 0.09 0.13 0.41 37.52