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. Author manuscript; available in PMC: 2017 Sep 15.
Published in final edited form as: Drug Dev Ind Pharm. 2014 Dec 8;41(7):1089–1094. doi: 10.3109/03639045.2014.927481

Table 2.

Antifungal activity of ITR and ITR-HCl on different fungus species.

Organisms ITR (μg/ml) ITR-HCl (μg/ml)


IC50 MIC MFC IC50 MIC MFC
T. rubrum 0.063 ± 0.02 0.26 ± 0.08 >20.0 0.06 ± 0.01 0.31 ± 0.05 >20.0
C. albicans 0.18 ± 0.07 >20.0 >20.0 0.11 ± 0.05 >20.0 >20.0
C. krusei 0.23 ± 0.03 0.87 ± 0.001 1.15 ± 0.25 0.27 ± 0.144 0.84 ± 0.005 1.04 ± 0.15
A. fumigatus 0.50 ± 0.17 1.04 ± 0.35 6.33 ± 1.35 0.29 ± 0.03 1.06 ± 0.25 6.67 ± 1.04
C. neoformans <0.02 0.027 ± 0.002 0.03 ± 0.001 <0.02 0.02 ± 0.002 0.03 ± 0.001

All the values are an average of n =3.