Skip to main content
. Author manuscript; available in PMC: 2017 Sep 15.
Published in final edited form as: Biomarkers. 2017 Jul 26;22(6):584–593. doi: 10.1080/1354750X.2017.1347961

Table 3.

Association between blood pressure measures with one-fold increase of histone modification level before worka.

Effect Obsb All participants Obsb Office workers Obsb Truck drivers
Estimate 95%CI p-Valuec Estimate 95%CI p-Valuec Estimate 95%CI p-Valuec
H3K9ac
 Systolic pressure 217 −2.52 −4.22, −0.81 <0.01* 103 −2.30 −4.88, 0.29 0.09 114 −4.02 −6.81, −1.23 0.01*
 Diastolic pressure 217 −1.12 −2.57, 0.34 0.14 103 −1.64 −3.75, 0.47 0.13 114 −0.87 −3.39, 1.66 0.50
 Mean arterial pressure 217 −1.54 −2.95, −0.14 0.03* 103 −1.84 −3.94, 0.26 0.09 114 −1.91 −4.24, 0.43 0.11
 Pulse pressure 217 −1.10 −2.44, 0.24 0.11 103 −0.58 −2.46, 1.31 0.55 114 −1.06 −3.35, 1.23 0.37
H3K9me3
 Systolic pressure 187 −2.04 −3.32, −0.77 <0.01* 93 −2.41 −1.19, −0.64 0.01* 94 −1.66 −3.67, 0.35 0.11
 Diastolic pressure 187 −1.68 −2.84, −0.52 0.01* 93 −2.36 −3.90, −0.83 0.01* 94 −0.44 −2.53, 1.65 0.68
 Mean arterial pressure 187 −1.75 −2.86, −0.64 <0.01* 93 −2.30 −3.82, −0.78 0.01* 94 −0.90 −2.79, 0.99 0.36
 Pulse pressure 187 −0.24 −1.16, 0.68 0.61 93 −0.22 −1.36, 0.93 0.71 94 −0.88 −2.57, 0.80 0.31
H3K27me3
 Systolic pressure 231 −2.28 −4.42, −0.13 0.04* 114 −1.96 −5.07, 1.16 0.22 117 −3.86 −7.42, −0.30 0.04*
 Diastolic pressure 231 −1.19 −3.06, 0.68 0.21 114 −1.84 −4.37, 0.70 0.16 117 −0.95 −4.33, 2.44 0.59
 Mean arterial pressure 231 −1.51 −3.28, 0.26 0.10 114 −1.85 −4.35, 0.65 0.15 117 −1.78 −4.81, 1.24 0.25
 Pulse pressure 231 −0.83 −2.57, 0.92 0.35 114 −0.23 −2.56, 2.11 0.85 117 −0.52 −3.72, 2.69 0.75
H3K36me3
 Systolic pressure 228 −1.46 −3.34, 0.43 0.13 113 −2.01 −4.87, 0.86 0.17 115 −1.06 −4.11, 1.99 0.50
 Diastolic pressure 228 −0.07 −1.69, 1.55 0.93 113 −0.06 −2.48, 2.35 0.96 115 0.03 −2.66, 2.72 0.98
 Mean arterial pressure 228 −0.49 −2.05, 1.06 0.53 113 −0.55 −2.86, 1.78 0.64 115 −0.30 −2.81, 2.21 0.81
 Pulse pressure 228 −0.96 −2.43, 0.50 0.20 113 −1.56 −3.72, 0.61 0.16 115 0.44 −1.97, 2.85 0.72
a

Adjusted for occupational group, sex, age, BMI, work hours per week, day of the week, smoking habits, number of cigarettes smoked during examination time, alcohol drinking status, temperature, and 8-day ambient PM10.

b

Number of non-missing observations used for analysis for histone modification measurements.

c

p-Values were calculated using mixed-effects regression models.