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. Author manuscript; available in PMC: 2017 Sep 15.
Published in final edited form as: Biomarkers. 2017 Jul 26;22(6):584–593. doi: 10.1080/1354750X.2017.1347961

Table 4.

Association between blood pressure measures with one-fold increase of histone modification level after worka.

Effect Obsb All participants Obsb Office workers Obsb Truck drivers
Estimate 95%CI p-Valuec Estimate 95%CI p-Valuec Estimate 95%CI p-Valuec
H3K9ac
 Systolic pressure 217 −0.53 −2.24, 1.17 0.54 103 0.72 −1.67, 3.10 0.56 114 −0.79 −3.81, 2.24 0.61
 Diastolic pressure 217 −1.00 −2.31, 0.31 0.14 103 −1.34 −3.25, 0.57 0.17 114 −0.36 −2.30, 1.58 0.72
 Mean arterial pressure 217 −0.81 −2.08, 0.46 0.21 103 −0.63 −2.49, 1.23 0.51 114 −0.45 −2.43, 1.53 0.66
 Pulse pressure 217 0.55 −0.95, 2.05 0.47 103 1.74 −0.50, 3.97 0.13 114 0.11 −2.22, 2.45 0.92
H3K9me3
 Systolic pressure 187 −0.51 −1.83, 0.81 0.45 93 −0.08 −1.83, 1.66 0.93 94 −0.18 −2.67, 2.30 0.89
 Diastolic pressure 187 −0.34 −1.46, 0.79 0.56 93 −0.62 −2.19, 0.95 0.44 94 −0.12 −1.80, 1.57 0.89
 Mean arterial pressure 187 −0.30 −1.36, 0.77 0.59 93 −0.33 −1.83, 1.18 0.67 94 0.08 −1.56, 1.74 0.92
 Pulse pressure 187 −0.18 −1.37, 1.02 0.77 93 −0.21 −1.87, 1.44 0.80 94 0.47 −1.56, 2.49 0.65
H3K27me3
 Systolic pressure 231 0.09 −2.06, 2.24 0.93 114 0.70 −2.18, 3.58 0.63 117 −0.15 −3.98, 3.67 0.94
 Diastolic pressure 231 −0.30 −1.98, 1.39 0.73 114 0.57 −1.76, 2.89 0.63 117 −2.38 −5.08, 0.32 0.09
 Mean arterial pressure 231 −0.16 −1.81, 1.49 0.85 114 0.60 −1.65, 2.86 0.60 117 −1.71 −4.46, 1.04 0.23
 Pulse pressure 231 0.14 −1.67, 1.96 0.88 114 −0.35 −3.00, 2.30 0.79 117 2.96 0.12, 5.81 0.04*
H3K36me3
 Systolic pressure 228 0.18 −1.70, 2.07 0.85 113 −0.02 −2.76, 2.73 0.99 115 1.22 −1.94, 4.38 0.45
 Diastolic pressure 228 0.05 −1.39, 1.49 0.95 113 0.00 −2.19, 2.20 1.00 115 −0.66 −2.81, 1.48 0.55
 Mean arterial pressure 228 0.16 −1.25, 1.57 0.82 113 0.15 −1.99, 2.28 0.89 115 0.06 −2.15, 2.26 0.96
 Pulse pressure 228 −0.18 −1.80, 1.43 0.83 113 −0.53 −3.04, 1.97 0.68 115 1.49 −0.87, 3.85 0.22
a

Adjusted for occupational group, sex, age, BMI, work hours per week, day of the week, smoking habits, number of cigarettes smoked during examination time, alcohol drinking status, temperature, and 8-day ambient PM10.

b

Number of non-missing observations used for analysis for histone modification measurements.

c

p-Values were calculated using mixed-effects regression models.