FIG 4.
ACBD3 is necessary for PI4KB localization in replication centers. (A) RD cells were mock infected or infected with EV71 at an MOI of 5 PFU/cell. After 8 h, the cells were fixed and labeled with anti-dsRNA (MAb J2) (green) and anti-3A (red) antibodies. (B and C) RD cells were treated as for panel A. The cells were labeled with anti-dsRNA (MAb J2) (green) and anti-ACBD3 (red) (B) or anti-PI4KB (red) (C) antibodies.