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SF162 gp140-mediated inhibition of CD3/TCR-induced CD4 T-cell proliferation is prevented by CD4bs occlusion. In each graph, bars are used to indicate the number of undivided cells (bar on the right) and the number of cells for each cell division within the CD3CD4 population. Note the difference in the fraction of undivided cells, which is increased after addition of SF162 gp140 (CD4bs-open) but not of SF162 gp140 (CD4bs-occluded).
