FIG 7.

HSV-1 latent DNA loads in trigeminal ganglia of mice treated with MAb CH42, CH43, or isotype control (A32) or human IVIG and infected with HSV-1 by corneal scarification. The mice were treated and infected as described in the legend to Fig. 4; mice not infected with HSV-1 (No inf) served as a negative control. Four weeks after infection, the mice were euthanized, trigeminal ganglia were harvested, DNA was isolated, and HSV-1 DNA copies per microgram of DNA were determined by real-time PCR using primers and a probe specific for the HSV-1 gG gene. The error bars indicate standard deviations.