Table 4.
Metabolites demonstrating >twofold changes and related to acylcarnitine and ketone body metabolism measured before and after a 4‐day, 51‐km cross‐country ski march
| Subpathway | Biochemical name | Fold change (POST/PRE) |
|---|---|---|
| Acylcarnitine | Hexanoylglycine | 2.54 |
| Acetylcarnitine (C2) | 2.43 | |
| 3‐Hydroxybutyrylcarnitine (1) | 25.05 | |
| 3‐Hydroxybutyrylcarnitine (2) | 4.01 | |
| Hexanoylcarnitine (C6) | 2.76 | |
| Octanoylcarnitine (C8) | 2.46 | |
| Decanoylcarnitine (C10) | 2.56 | |
| Cis‐4‐decenoylcarnitine (C10:1) | 2.20 | |
| Laurylcarnitine (C12) | 3.28 | |
| Myristoylcarnitine (C14) | 2.60 | |
| Palmitoleoylcarnitine (C16:1)a | 3.06 | |
| Myristoleoylcarnitine (C14:1)a | 4.40 | |
| Suberoylcarnitine (C8‐DC) | 7.61 | |
| Adipoylcarnitine (C6‐DC) | 6.32 | |
| Arachidoylcarnitine (C20)a | 2.49 | |
| Erucoylcarnitine (C22:1)a | 3.94 | |
| Ketone bodies | Acetoacetate | 20.59 |
| 3‐Hydroxybutyrate | 31.25 |
Data are fold changes calculated using the mean for each time point. Repeated measures ANOVA (n = 24) used to examine main effect of time, diet, and their interaction on metabolites measure before (PRE) and after (POST) military training. P values were adjusted using the Benjamini–Hochberg correction (Q); main effect of time, Q < 0.10 for all. All diet by time interactions were not statistically significant (Q > 0.20). Metabolites in bold font are those with the strongest influence on prediction accuracy in the random forest analysis (see Fig. 1B).
Compounds that have not been officially confirmed based on a standard, but are identified with high confidence.