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. 2017 Aug 25;117(17):11570–11648. doi: 10.1021/acs.chemrev.7b00287

Figure 58.

Figure 58

Structure of the monomer (left) and dimer (right) of germacradien-4-ol synthase; aspartate-rich and NSE metal-binding motifs are red and orange, respectively. The location of the E248A mutation required to facilitate crystallization is indicated by a white band. Reproduced from ref (279). Copyright 2016 American Chemical Society.