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. 2017 Aug 25;117(17):11570–11648. doi: 10.1021/acs.chemrev.7b00287

Figure 69.

Figure 69

Possible reaction mechanisms for the cyclization of FPP to form the tricyclic sesquiterpene pentalenene. Pathway B is most consistent with all available enzymological data and chemical theory. Reproduced from ref (362). Copyright 2012 American Chemical Society.