Table 4.
Stratified analysis of genotypes of ErbB3 rs3202538 with clinicopathological parameters of GC
| Features | Genotype | GG vs GT P value* |
GG vs TT P value* |
||
|---|---|---|---|---|---|
| GG | GT | TT | |||
| Age (years) | 0.167 | 0.081 | |||
| ≤50 | 81 | 161 | 134 | ||
| >50 | 97 | 156 | 222 | ||
| Gender | 0.416 | 0.756 | |||
| Male | 75 | 137 | 145 | ||
| Female | 103 | 219 | 211 | ||
| Hp. infection | 0.002 | 0.169 | |||
| Negative | 48 | 129 | 77 | ||
| Positive | 130 | 188 | 279 | ||
| Differentiation grade | 0.0047 | <0.0001 | |||
| Well | 73 | 94 | 47 | ||
| Moderate | 68 | 117 | 120 | ||
| Poor | 37 | 106 | 189 | ||
| Tumor size (cm) | 0.109 | <0.0001 | |||
| ≤3 | 93 | 164 | 19 | ||
| >3 | 85 | 153 | 337 | ||
| Metastasis | 0.0042 | <0.0001 | |||
| Yes | 49 | 128 | 235 | ||
| No | 129 | 189 | 121 | ||
* Two-sided Chi square test for either genotype distributions or allele frequencies between cases and controls