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. 2017 Sep 3;13(8):1082–1091. doi: 10.7150/ijbs.20905

Table 2.

Comparison of the expression patterns of canonical Wnt signaling pathway between mouse, pig and human

stage tissues/cells species
mouse pig human
cap stage -bell stage enamel knot / IEE Wnt3, Wnt4, Wnt6, Wnt7b [24], Wnt5a [12], Wnt10a, Wnt10b [29],
β-catenin [5], Axin2 [10], Lef1 [30]
Wnt3a, Wnt5a,
β-catenin, Axin2, Lef1
Wnt5a [31,32], Wnt3, Dkk1, Sostdc1 [32],
β-catenin, Lef1, Tcf4 [32]
dental papilla Wnt5a [24,25], Dkk1 [11], Sostdc1 [33],
β-Catenin [5], Axin2 [10], Lef1 [30], Tcf1 [34]
Wnt5a, Dkk1,
β-catenin, Axin2, Lef1, Tcf4
Dkk1, Sostdc1 [32],
β-Catenin, Lef1, Tcf4 [32]
secretory stage ameloblast β-Catenin [9], Axin2 [34] Wnt3a, Wnt5a
odontoblast/
pre-odontoblast
Wnt5a [25], Wnt11 [35], Dkk1 [11,14], β-Catenin [36], Axin2 [34] Wnt5a, Dkk1,
Lef1, Tcf4
Wnt5a [31]
dental papilla Wnt11 [35], Dkk2, Dkk3 [34] Wnt5a, Dkk1