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. 2017 Aug 18;14(10):1002–1007. doi: 10.7150/ijms.20809

Figure 1.

Figure 1

IWP-2 inhibits IL-36γ-induced expression of cyclinD1 and ki-67 in HaCaT cells. HaCaT cells were incubated with IL-36γ (100 ng/mL) for 24 h and 48 h in the presence or absence of IWP-2 (1 μM). IL-36γ exposure induced cyclinD1 and ki-67 upregulation. Treatment with IWP-2 significantly blunted IL-36γ induced cyclinD1 and ki-67 upregulation at mRNA level. ∗P < 0.05 vs. Control group; #P < 0.05 vs. IL-36γ group.