Figure 3.

Logistic regression of the probability of overall response vs AUC_ss. Black line indicates the predicted response. Light blue ribbon indicates 95% confidence interval of predicted response. Black solid squares and vertical error bars indicate mean and 95% confidence interval for the observed response rate within each quartile of exposure. Individual exposure values are shown as colored squares (red squares represent responders and blue squares represent nonresponders). AUC_ss indicates area under the concentration‐time curve at steady state.