Table 1.
Baseline Demographics and Patient Characteristics
| Variable | Myomectomy | UAE | Lap-RFA | MRg-FUS | Hysterectomy |
|---|---|---|---|---|---|
| Mean age, y (range) | 37.4**** (32.0–43.2) | 41.7*** (32.4–47.1) | 41.5*** (39.2–43.6) | 43.3** (35.6–46.0) | 45.6 (44.2–49.3) |
| Cohorts, n | 24 | 16 | 6 | 10 | 10 |
| Patients, n | 3915 | 1248 | 269 | 801 | 519365 |
| References | 10, 23–36 | 10, 21, 22, 26, 30, 31, 37–43 | 36, 44–47 | 21, 22, 47–54 | 30, 31, 36, 37, 55, 56 |
| Mean BMI, kg/m2 (range) | 24.0* (20.4–27.2) | 26.6 (23.0–28.4) | 30.4 (29.5–30.9) | 25.2 (21.6–25.9) | 27.8 (24.8–30.5) |
| Cohorts, n | 18 | 4 | 2 | 5 | 6 |
| Patients, n | 1581 | 253 | 127 | 571 | 529 |
| References | 23, 24, 27, 28, 30, 32–36 | 30, 37, 43 | 44 | 30, 36, 37, 56 | 30, 36, 37, 56 |
| Race, % (95% CI) | |||||
| Caucasian | 39.5 (10.9, 72.9) | 58.3 (24.4, 88.2) | 26.3 (2.0, 64.6) | 20.0 (0.56, 56.7) | 70.4 (61.3, 78.7) |
| Black | 22.3 (5.7, 45.8) | 12.4 (1.1, 33.4) | 4.2 (0.9, 23.7) | 5.0 (0.46, 14.1) | 14.5 (8.1, 22.6) |
| Other | 29.3 (0.43, 77.7) | 22.5 (2.0, 55.8) | 63.6 (14.5, 98.7) | 72.2 (25.2, 99.6) | 14.3 (12.0, 16.8) |
| Cohorts, n | 9 | 8 | 6 | 8 | 5 |
| Patients, n | 858 | 589 | 269 | 715 | 519,023 |
| References | 23, 26, 27, 30, 35, 37 | 21, 26, 30, 37, 39, 42, 43 | 44–47, 57 | 21, 47–52, 54 | 30, 37, 55 |
| Mean parity (range) | 0.6 (0.07–1.1) | 0.8 | 1.1 (1.0–1.1) | 2.0 (1.9–2.2) | |
| Cohorts, n | 5 | 1 | 0 | 2 | 4 |
| Patients, n | 674 | 87 | 372 | 334 | |
| References | 23, 26, 32, 36 | 26 | 48, 51 | 36, 56 | |
| Mean baseline HRQL (range) | 42.2 (37.3–46.4) | 41.8 (40.2–42.9) | 40.9 (37.3–60.2) | 47.0 | 40.9 |
| Cohorts, n | 3 | 2 | 4 | 1 | 1 |
| Patients, n | 159 | 181 | 216 | 109 | 106 |
| References | 25, 30, 57 | 25, 30 | 44–46, 57 | 49 | 30 |
| Mean baseline SSS (range) | 61.2 (55.9–70.2) | 62.9 (59.8–65.1) | 60.8 (43.6–77.2) | 61.7 | 64.9 |
| Cohorts, n | 3 | 2 | 4 | 1 | 1 |
| Patients, n | 159 | 181 | 216 | 109 | 106 |
| References | 14, 52, 69 | 52, 69 | 14, 18, 27, 62 | 101 | 69 |
| Mean baseline EQ-5D | 72.3 | 70.0 | 76.4 | ||
| Cohorts, n | 1 | 1 | 2 | 0 | 0 |
| Patients, n | 25 | 106 | 151 | ||
| References | 57 | 38 | 44, 57 |
UAE = uterine artery embolization; Lap-RFA = laparoscopic radiofrequency ablation; MRg-FUS = magnetic resonance-guided focused ultrasound; BMI = body mass index; CI = confidence interval; HRQL = health-related quality of life; SSS = symptom severity score; EQ-5D = EuroQol-5D.
*P < .10,
**P < .05,
***P < .01,
****P < .001, hysterectomy results vs all other interventions.