Calculating persistence length based on the worm-like chain model reveals that F10 in the presence of potassium exhibits the most local stability while F10 in calcium chloride exhibits the least. Since F10’s persistence length is smaller when solvated in 150mM NaCl than in 150mM KCl, we predict that a strand of F10 would less compact inside of a cell than outside. We also predict that a calcium-rich environment would induce the most compact structures of F10 while a potassium-rich one would induce the least compact.