Table 2.
Chlamydia trachomatis Seropositivity by Race, Serologic Measure, and Tubal Factor Infertility (TFI) Case Status based on HSG Case Definitiona
| Serologic Measure used to Determine Chlamydia trachomatis Seropositivity | |||||||
|---|---|---|---|---|---|---|---|
| Study Group | N | Positive by Medac IgG MOMP n (%, 95% CI) |
Positive by EB-ELISA (IgG1 or IgG3) n (%, 95% CI) |
Positive by EB-ELISA IgG1 n (%, 95% CI) |
Positive by EB ELISA IgG3 n (%, 95% CI) |
Positive by Medac IgG MOMP or EB ELISAb n (%, 95% CI) |
Positive by Medac IgG MOMP and EB ELISA n (%, 95% CI) |
| Black Race | |||||||
| Overall | 107c | 51 48% (38%–58%) |
85 79% (71%–88%) |
83 78% (69%–86%) |
67 63% (53%–72%) |
87 81% (73%–89%) |
49 46% (36%–56%) |
| Cases | 47c | 22 48% (32%–63%) |
38 81% (69%–93%) |
36 77% (63%–90%) |
27 57% (42%–73%) |
39 83% (71%–95%) |
21 46% (30%–61%) |
| Controls | 60 | 29 48% (35%–62%) |
47 78% (67%–90%) |
47 78% (67%–90%) |
40 67% (54%–79%) |
48 80% (69%–91%) |
28 47% (33%–60%) |
| Non-Black Race | |||||||
| Overall | 620 | 106 17% (14%–20%) |
146 24% (20%–27%) |
97 16% (13%–19%) |
95 15% (12%–18%) |
194 31% (28%–35%) |
58 9% (7%–12%) |
| Cases | 140 | 31 22% (15%–29%) |
43 31% (23%–39%) |
29 21% (14%–28%) |
35 25% (17%–33%) |
52 37% (29%–46%) |
22 16% (9%–22%) |
| Controls | 480 | 75 16% (12%–19%) |
103 21% (18%–25%) |
68 14% (11%–17%) |
60 13% (9%–16%) |
142 30% (25%–34%) |
36 8% (5%–10%) |
HSG, hysterosalpingogram; MOMP, major outer membrane protein; CI, confidence interval; EB, elementary body; ELISA, enzyme-linked immunosorbent assay
a
TFI case=unilateral or bilateral fallopian tube blockage on HSG; Control=bilateral patent tubes and no other tubal abnormalities on HSG, no prior history of tubal ectopic pregnancy or surgery to repair blocked tubes
b
Primary definition of C. trachomatis seropositivity
c
Medac IgG MOMP result was not available for one participant.