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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Am J Obstet Gynecol. 2017 May 19;217(3):336.e1–336.e16. doi: 10.1016/j.ajog.2017.05.026

Table 3.

Crude Odds Ratios for Association between Chlamydia trachomatis Seropositivity and Tubal Factor Infertility (TFI), by Race, Serologic Measure, and TFI Case Definition

Serologic Measure used to Determine Chlamydia trachomatis Seropositivity
Case Definition (by Race) N Positive by Medac IgG MOMP
OR (95% CI)a 		Positive by EB-ELISA (IgG1 or IgG3)
OR (95% CI)a 		Positive by EB-ELISA IgG1
OR (95% CI)a 		Positive by EB ELISA IgG3
OR (95% CI)a 		Positive by Medac IgG MOMP or EB ELISA
OR (95% CI)a 		Positive by Medac IgG MOMP and EB ELISA
OR (95% CI)a
Black Race
HSG case definitionb 107c 0.98
(0.45–2.11)		 1.17
(0.45–3.02)		 0.91
(0.36–2.26)		 0.68
(0.31–1.49)		 1.22
(0.45–3.28)		 0.96
(0.44–2.07)
Expanded case definitiond 117c 0.93
(0.45–1.92)		 1.04
(0.43–2.51)		 0.85
(0.36–2.01)		 0.74
(0.35–1.57)		 1.18
(0.46–2.98)		 0.86
(0.41–1.78)
Laparoscopy case definitione 31 1.13 2.95
(0.48–18.3)		 2.95
(0.48–18.3)		 1.50
(0.36–6.23)		 1.50
(0.21–10.5)		 1.93
(0.44–8.33)
Non-Black Race
HSG case definitionb 620 1.54
(0.96–2.45)		 1.62
(1.07–2.47) 		1.58
(0.98–2.56)		 2.33
(1.46–3.73) 		1.41
(0.95–2.09)		 2.30
(1.30–4.06)
Expanded case definitiond 654 1.61
(1.05–2.48) 		1.78
(1.21–2.62) 		1.81
(1.17–2.80) 		2.37
(1.53–3.66) 		1.56
(1.09–2.25) 		2.37
(1.39–4.01)
Laparoscopy case definitione 138 3.04
(1.27–7.29) 		2.13
(1.01–4.50) 		2.24
(0.91–5.49)		 3.74
(1.58–8.87) 		1.90
(0.94–3.85)		 5.44
(1.71–17.3)

OR, odds ratio; HSG, hysterosalpingogram; MOMP, major outer membrane protein; CI, confidence interval; EB, elementary body; ELISA, enzyme-linked immunosorbent assay

a

Statistically significant results (P<0.05) are indicated by bold print.

b

TFI case=unilateral or bilateral fallopian tube blockage on HSG; Control=bilateral patent tubes and no other tubal abnormalities on HSG and no prior history of tubal ectopic pregnancy or surgery to repair blocked tubes

c

Medac IgG MOMP result was not available for one participant

d

TFI case=unilateral or bilateral fallopian tube blockage or other tubal abnormalities on HSG, or prior history of tubal ectopic pregnancy, hydrosalpinx, or surgery to repair blocked tubes; Control=bilateral patent tubes and no other tubal abnormalities on HSG and no prior history of tubal ectopic pregnancy or surgery to repair blocked tubes

e

TFI case=laparoscopy showing evidence of tubal damage; Control=laparoscopy within one year of study showing no evidence of tubal damage